MOnica Risk, Genetics, Archiving and Monograph (Network) (MORGAM)

In the WHO MONICA Project, standardized surveys of cardiovascular risk factors were carried out in defined populations in 21 countries in the 1980s and 1990s. Many of the MONICA Centres have followed up their Cohorts of the survey respondents. MORGAM is a research collaboration between several MONICA and other similar centres to bring together the baseline and follow-up data as well as biosamples for joint analysis.

MORGAM is a multinational collaborative study exploring the relationships between the development of cardiovascular diseases, their classic and genetic risk factors and biomarkers. The strengths of MORGAM are population based cohorts representing different parts of Europe with highly standardized baseline measurements, long follow-up, thorough harmonization and documentation of the data, and a wide network of collaborative researchers.

General Information

General Design

Study design: 

Network of cohorts

Marker Paper

Marker paper: 
Evans A et al. MORGAM (an international pooling of cardiovascular cohorts). Int J Epidemiol 2005.
Pubmed ID: 

Supplementary Information

Endpoints (N incident cases)

Head and Neck (C00-C14; C31, C32) = NA
Esophagus (C15) = NA
Stomach (C16) = NA
Colorectal (C18-21) = NA
Liver (C22) = NA
Gallbladder (C23-24) = NA
Pancreas (C25) = NA
Lung (C33-34) = NA
Breast (C50) = NA
Cervix (C53) = NA
Corpus uteri (C54) = NA
Ovary (C56-57) = NA
Prostate (C61) = NA
Total cancers (C00-C97) excluding non-melanoma skin cancer = 8099

Cardiovascular endpoints
Acute coronary events = 20479
Stroke = 11672

Other endpoints
Type II diabetes (E11) = 7383


Participating countries

The following countries are represented in the MORGAM network:

  • Australia
  • Czech Republic
  • Denmark
  • Estonia
  • Finland
  • France
  • Germany
  • Italy
  • Lithuania
  • Norway
  • Poland
  • Russian Federation
  • Spain
  • Sweden
  • United Kingdom


Other useful information