Health 2000 (HEALTH 2000)

Health 2000 was a health interview/examination survey carried out in Finland in 2000 and 2001.

The main aim of the survey was to obtain up-to-date information on the most important public health problems in the country, their causes and treatment as well as on the population’s functional capacity and working capacity.

 

General Information

General Design

Study design: 
Cohort study
General Information on Follow Up (profile and frequency): 

Information from registries and national health records yearly from 2000 to 2011, re-examination (HEALTH 2011 survey) in 2011-2012.
Date of last follow-up: 31 December 2011.

Recruitment target: 
Individuals
Target number of participants: 
8 028
Target number of participants with biological samples: 
6 771
Supplementary information about target number of participants: 

The Health 2000 study collected the following biospecimen at baseline:

  • Blood: 6771 participants
  • Plasma: 6771 participants
  • Serum: 6771 participants
  • DNA: 6771 participants
  • Urine: 6771 participants
  • Fecal: ~800 participants

 

The following biospecimen were collected during follow-up (2011):

  • Blood: 4 664 participants
  • Plasma: 4 664 participants
  • Serum:    4 664 participants
  • DNA: about 200 participants (only those who did not provide DNA at baseline)

Access

Access to external researchers or third parties provided or foreseen for
Data (questionnaire-derived, measured...): 
Yes
Biological samples: 
Yes

Supplementary Information

Endpoints (N incident cases)

Cancer
Head and Neck (C00-C14; C31, C32) = 30
Esophagus (C15) = 11
Stomach (C16) = 31
Colorectal (C18-21) = 109
Liver (C22) = 16
Gallbladder (C23-24) = 13
Pancreas (C25) = 28
Lung (C33-34) = 75
Breast (C50) = 218
Cervix (C53) = 6
Corpus uteri (C54) = 39
Ovary (C56-57) = 33
Prostate (C61) = 105
Total cancers (C00-C97) excluding non-melanoma skin cancer = NA

Cardiovascular endpoints
Acute coronary events = 2877
Stroke = 283

Other endpoints
Type II diabetes (E11) = 481

A detailed list of endpoint incident cases can be downloaded from the Documents section.

 

Supplementary information about access

The Scientific Board of Health 2000 approves all proposed studies. A research plan is required.

Review procedure:

  • Specify criteria considered to review access requests.
  • Scientific merit of proposed study (clarity, novelty and scientific excellence);  
  • Ethical requirements; 
  • Qualifications of applicant;  
  • Applicant’s privacy and confidentiality policy and security measures; 
  • Compatibility of proposed study with the cohort’s/biobank’s objectives;  
  • Overlapping initiatives between proposed study and studies already approved;
  • Adequacy of applicant’s resources to carry out the proposed project; 
  • Quantity of samples requested;
  • Impact on future uses of data and samples; 
  • Impact on biobank as a resource (potential to enrich biobank)

Conditions for access:

  • Cooperation
  • Co-authorship
  • Intellectual property of findings from resources of the individual biobank /study
  • Return data to the individual biobank / study in order to increase the scientific value of samples
  • In case of complicated data extraction cost recovery may apply

Documents

Authorization

Authorization from contributors to the BbmriLpc.IARC Catalogues: 
Seppo Koskinen authorised the contribution to BbmriLpc.IARC on Friday, March 14, 2014

Datasets

NameDescription
Health2000

Exposure data collected at baseline in the...